Peptide Database

Peptide NameStem bromelain

Function Ontology

Anticancer

Antimicrobial

Hemostasis ▸ Fibrinolytic activity

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length212 amino acids

Chemical FormulaC1024H1567N269O304S10

DescriptionStandard

        AVPQSIDWRDYGAVTSVKNQNPCGACWAFAAIATVESIYKIKKGILEPLSEQQVLDCAKGYGCKGGWEFRAFEFIISNKGVASGAIYPYKAAKGTCKTDGVPNSAYITGYARVPRNNESSMMYAVSKQPITVAVDANANFQYYKSGVFNGPCGTSLNHAVTAIGYGQDSIIYPKKWGAKWGEAGYIRMARDVSSSSGICGIAIDPLYPTLEE
    

Molecular Weight22830.67 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)3.82

Net Charge (pH 7.4) 3.42

Charge Density (pH 7.0) 0.0180

GRAVY Index-0.16

Hydrophobic Moment 0.62

Boman Index0.10

Instability Index26.22

Aliphatic Index 73.25

Aromaticity 0.1179

Extinction Coeff. Reduced 48360.00

Extinction Coeff. Oxidized 48735.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0082678 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Mus musculus [Animal]; Rattus norvegicus [Animal]; Sus scrofa [Animal]; Escherichia coli [Bacterium]

FamilyInterleukin

Tax ID9606;10090;10116;9823;562

Structure & Mods

Configcyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anticancer Immunomodulatory Coagulation factor replacement Enzyme replacement Thrombolytic Fibrinolytic

TargetCHO

Half-LifeThe estimated plasma half-life of stem bromelain is 6-9 hours [A32644].