Peptide Database

Peptide NameSLAY-screened peptide P1517

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC62H106N26O21S

DescriptionStandard

        ANKRGNPCQRPNATG
    

Molecular Weight1583.73 Da

Isoelectric Point (pI)10.86

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.58

Charge Density (pH 7.0) 0.1857

GRAVY Index-1.70

Hydrophobic Moment 0.41

Boman Index-0.47

Instability Index30.74

Aliphatic Index 13.33

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 795.55

LogP -13.64

H-bond Donors 27.0

H-bond Acceptors 25.0

Rotatable Bonds 50.0

Heavy Atoms 110.0

Ring Count 2.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0327377 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/