Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length445 amino acids

Chemical FormulaC2262H3530N572O655S16

DescriptionStandard

        MCTKIIPVLWGCFLLWNLYISSSQTIYPGIKARITQRALDYGVQAGMEMIEQMLKQKNLPDLSGSESLEFLKVDYVNYNFSNIKINAFSFPNTSLAFVPGVGIKALTNHGTANISTDWEFKSPIFQDTGGADLFLSGVYFTGIIILTRNDFGHPILKLQDCYAQVSHAHISFSGELSVLYNSFAEPMEKPILKNLNEMLCPIIANEVEALNANLSTLEVLTKIDNYTLLDYSLISSPEITENYLDLNLKISNHFVQNSQGLGNVLSRIAEIYILSQPFMVRIMATEPPVINLQPGNFTLDIPASIMMLTQTNNSTVETIVSMDFVASTSVGLVILGQRLVCSLSLNRFRLTLPESNRSNIEVLRFENILSSILHFGVLPLANAKLQQGFPLPNPHKISFVNSDIEVFEGFLLISTDLKYETSSKQHPSFHGWEGLNLINGWWRGK
    

Molecular Weight49730.70 Da

Isoelectric Point (pI)5.42

Net Charge (pH 7.0)-9.71

Net Charge (pH 7.4) -10.55

Charge Density (pH 7.0) -0.0218

GRAVY Index0.13

Hydrophobic Moment 0.68

Boman Index0.17

Instability Index36.60

Aliphatic Index 105.80

Aromaticity 0.0989

Extinction Coeff. Reduced 52370.00

Extinction Coeff. Oxidized 52620.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0304717 VERIFIED: NO

Provenance & Taxonomy

OrganismSapajus apella (Brown-capped capuchin) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria