Peptide Database

Peptide NameUnnamed

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Reproductive neuropeptide

Regulatory peptide ▸ Biological regulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length69 amino acids

Chemical FormulaC351H552N98O109S3

DescriptionStandard

        QYWSYGVRPGGKRNIEPLVDSFQEMAKEIDQLAEPQHFECTLHQPRSPLRDLKGALESLMEEETGQKKI
    

Molecular Weight7984.92 Da

Isoelectric Point (pI)5.28

Net Charge (pH 7.0)-3.05

Net Charge (pH 7.4) -3.40

Charge Density (pH 7.0) -0.0443

GRAVY Index-0.91

Hydrophobic Moment 0.69

Boman Index-0.15

Instability Index77.89

Aliphatic Index 69.28

Aromaticity 0.0725

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3360.09

LogP -31.54

H-bond Donors 113.0

H-bond Acceptors 111.0

Rotatable Bonds 270.0

Heavy Atoms 561.0

Ring Count 13.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006198 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0275791 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyProgonadoliberin

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Growth regulation Development regulation

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0290443 VERIFIED: NO

Provenance & Taxonomy

OrganismCavia porcellus [Animal]

FamilyGnRH

Tax ID10141

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Other ModsGly10 Amidation

Bio-Activity Profile

Function

Hormone Reproductive neuropeptide