Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC85H131N25O25S9

DescriptionStandard

        GCRFCCGCCPEMVGCGVCCNF
    

Molecular Weight2191.69 Da

Isoelectric Point (pI)5.95

Net Charge (pH 7.0)-0.32

Net Charge (pH 7.4) -0.64

Charge Density (pH 7.0) -0.0151

GRAVY Index1.01

Hydrophobic Moment 0.32

Boman Index0.26

Instability Index15.77

Aliphatic Index 27.62

Aromaticity 0.0952

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 778.82

LogP -9.88

H-bond Donors 34.0

H-bond Acceptors 34.0

Rotatable Bonds 66.0

Heavy Atoms 144.0

Ring Count 3.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0279107 VERIFIED: YES

Provenance & Taxonomy

OrganismDichotomyctere nigroviridis [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)