Peptide Database

Peptide Namevhl-1

Function Ontology

Antiparasitic ▸ Anthelminthic

Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC128H209N33O43S6

DescriptionStandard

        SISGESCAMISCFTEVIGCSCKNKVCYLN
    

Molecular Weight3090.61 Da

Isoelectric Point (pI)5.85

Net Charge (pH 7.0)-0.59

Net Charge (pH 7.4) -0.87

Charge Density (pH 7.0) -0.0202

GRAVY Index0.56

Hydrophobic Moment 0.40

Boman Index0.19

Instability Index59.30

Aliphatic Index 77.24

Aromaticity 0.0690

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1232.55

LogP -15.57

H-bond Donors 48.0

H-bond Acceptors 49.0

Rotatable Bonds 103.0

Heavy Atoms 210.0

Ring Count 2.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0166250 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Tax ID97441

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Nematocidal Anthelmintic

TargetTrichostrongylus colubriformis

Activity5.78

MethodIC50

RECORD: Rec_0208534 VERIFIED: YES