Peptide Database

Peptide NameHistatin-1 (Histidine-rich protein 1) (Post-PB protein) (PPB) [Cleaved into: His1-(31-57)-peptide (His1 31 57) (His1-(12-38)-peptide) (His1 12 38) (Histatin-2)]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length57 amino acids

Chemical FormulaC320H461N89O82S3

DescriptionStandard

        MKFFVFALVLALMISMISADSHEKRHHGYRRKFHEKHHSHREFPFYGDYGSNYLYDN
    

Molecular Weight6962.83 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)2.11

Net Charge (pH 7.4) 1.52

Charge Density (pH 7.0) 0.0371

GRAVY Index-0.65

Hydrophobic Moment 0.39

Boman Index-0.06

Instability Index38.24

Aliphatic Index 56.49

Aromaticity 0.1930

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2748.85

LogP -19.89

H-bond Donors 98.0

H-bond Acceptors 94.0

Rotatable Bonds 227.0

Heavy Atoms 494.0

Ring Count 19.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418023 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyHistatin statherin

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Non-hemolytic

TargetNo Target Organism Found