Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length123 amino acids

Chemical FormulaC594H964N168O187S8

DescriptionStandard

        MKLLLLALPILVLLPQVIPAYSGEKKCWNRSGHCRKQCKDGEAVKETCKNLRACCVPSNEDHRRLPTTSPTPLSDSTPGIIDNILTIRFTTDYFEISSKKDMVEESEAEQGTQTSPPNVHHTS
    

Molecular Weight13707.54 Da

Isoelectric Point (pI)6.88

Net Charge (pH 7.0)-0.19

Net Charge (pH 7.4) -0.73

Charge Density (pH 7.0) -0.0015

GRAVY Index-0.50

Hydrophobic Moment 0.64

Boman Index-0.08

Instability Index61.29

Aliphatic Index 78.46

Aromaticity 0.0407

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5694.54

LogP -63.36

H-bond Donors 200.0

H-bond Acceptors 199.0

Rotatable Bonds 452.0

Heavy Atoms 957.0

Ring Count 20.0

Amide Bonds 131.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0398230 VERIFIED: NO

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyBeta-defensin; Defensin

Tax ID9555

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic