Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length83 amino acids

Chemical FormulaC435H678N124O117S10

DescriptionStandard

        MKFLFLFLVILLATEPMVSGRHHTLRCMGNTGVCRPSCRRTEHPYLYCLNYQPCCLQSYMRISIAGREEKDDWSQENRWPKIP
    

Molecular Weight9837.45 Da

Isoelectric Point (pI)8.86

Net Charge (pH 7.0)3.71

Net Charge (pH 7.4) 3.24

Charge Density (pH 7.0) 0.0447

GRAVY Index-0.34

Hydrophobic Moment 0.48

Boman Index-0.06

Instability Index70.82

Aliphatic Index 73.98

Aromaticity 0.1084

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3870.29

LogP -32.55

H-bond Donors 142.0

H-bond Acceptors 134.0

Rotatable Bonds 317.0

Heavy Atoms 686.0

Ring Count 20.0

Amide Bonds 88.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0161264 VERIFIED: NO

Provenance & Taxonomy

OrganismNeovison vison [Animal]

FamilyDefensin

Structure & Mods

Configdisulfide-stabilized peptide with linear backbone [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin

MethodQualitative functional evidence

RECORD: Rec_0419425 VERIFIED: NO

Provenance & Taxonomy

OrganismMustela putorius furo [Animal]

FamilyDefensin

Tax ID9669

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence