Peptide Database

Peptide NameLysozyme (EC 3.2.1.17)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Glycosidase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length177 amino acids

Chemical FormulaC858H1363N253O250S11

DescriptionStandard

        MTQKLHYGLSVAVLALIAAGASAPEIIDQFLDEKEGNHTTAYRDGAGIWTICRGAIMVDGKPVVPGMKLSKEKCDQVNAIERDKALAWVEKNIRVPLTEPQKAGIASFCPYNIGPGKCFPSTFYKRINAGDRRGACEAIRWWIKDGGRDCRIRSNNCYGQVSRRDQESALACWGIDR
    

Molecular Weight19575.26 Da

Isoelectric Point (pI)8.93

Net Charge (pH 7.0)5.62

Net Charge (pH 7.4) 5.13

Charge Density (pH 7.0) 0.0317

GRAVY Index-0.35

Hydrophobic Moment 0.72

Boman Index-0.04

Instability Index44.66

Aliphatic Index 78.36

Aromaticity 0.0791

Extinction Coeff. Reduced 34950.00

Extinction Coeff. Oxidized 35450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8120.29

LogP -85.90

H-bond Donors 291.0

H-bond Acceptors 269.0

Rotatable Bonds 650.0

Heavy Atoms 1372.0

Ring Count 29.0

Amide Bonds 189.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0116238 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyLysozyme

Tax ID585034

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Glycosidase Hydrolase Non-hemolytic

MethodQualitative functional evidence