Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC729H1166N208O213S14

DescriptionStandard

        MLFWIMLLLRRFMVDGGTDFFWNLEDGQWMTIAGRSDTPLEDQLTNQELRVDRREQLSQCKRNSCPNTARPRKCFSNITGYCRKKCEMGEIYEVACRNGKLCCVNEGENKKHKKAPKSPSFLVQPDGKMDYVILPTTTLLTIQI
    

Molecular Weight16701.23 Da

Isoelectric Point (pI)8.81

Net Charge (pH 7.0)4.53

Net Charge (pH 7.4) 4.10

Charge Density (pH 7.0) 0.0314

GRAVY Index-0.52

Hydrophobic Moment 0.58

Boman Index-0.12

Instability Index50.52

Aliphatic Index 71.74

Aromaticity 0.0833

Extinction Coeff. Reduced 20970.00

Extinction Coeff. Oxidized 21470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6871.08

LogP -67.15

H-bond Donors 245.0

H-bond Acceptors 233.0

Rotatable Bonds 564.0

Heavy Atoms 1164.0

Ring Count 23.0

Amide Bonds 158.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0271996 VERIFIED: NO

Provenance & Taxonomy

OrganismFelis catus [Animal]

FamilyDefensin

Tax ID9685

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence