Peptide Database

Peptide NameCircular bacteriocin; circularin A uberolysin family

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length64 amino acids

Chemical FormulaC297H500N74O84S2

DescriptionStandard

        MSQAVATTVVSIVLTGSTLVSMILGITAILSGGVDAILEIGWSAFVATVKKIVAERGKKAAIAW
    

Molecular Weight6515.72 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)1.50

Net Charge (pH 7.4) 1.28

Charge Density (pH 7.0) 0.0235

GRAVY Index1.10

Hydrophobic Moment 0.46

Boman Index0.41

Instability Index23.53

Aliphatic Index 135.62

Aromaticity 0.0469

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2491.93

LogP -20.88

H-bond Donors 90.0

H-bond Acceptors 88.0

Rotatable Bonds 217.0

Heavy Atoms 457.0

Ring Count 5.0

Amide Bonds 64.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0337628 VERIFIED: NO

Provenance & Taxonomy

OrganismGeobacillus icigianus [Bacterium]

FamilyBacteriocin

Tax ID1430331

Structure & Mods

Confighead-to-tail cyclic bacteriocin scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsCyclized peptide scaffold annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Non-hemolytic Non-ribosomal