Peptide Database

Peptide NameOfatumumab

Function Ontology

Anticancer

Standard StatusStandard

Sequence Length60 amino acids

Chemical FormulaC288H436N80O86S2

DescriptionStandard

        EVQLVESGGGLVQPGRSLRLSCAASGFTFNDYAMHWVRQAPGKGLEWVSTISWNSGSIGY
    

Molecular Weight6459.16 Da

Isoelectric Point (pI)6.85

Net Charge (pH 7.0)-0.08

Net Charge (pH 7.4) -0.33

Charge Density (pH 7.0) -0.0014

GRAVY Index-0.10

Hydrophobic Moment 0.56

Boman Index0.14

Instability Index50.30

Aliphatic Index 76.33

Aromaticity 0.1167

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2657.82

LogP -29.18

H-bond Donors 95.0

H-bond Acceptors 89.0

Rotatable Bonds 206.0

Heavy Atoms 456.0

Ring Count 13.0

Amide Bonds 64.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0395380 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyMonoclonal antibody

Tax ID9606

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Monoclonal antibody

Half-Lifeapprox. 14 d. Range: 2.3 to 61.5 d

PaperPubMed-linked source references: PMID:24090587; PMID:20140276; PMID:16810345; PMID:28314744; PMID:28273376; PMID:28269762; PMID:28257752; PMID:28236475; PMID:28213687 PMID24090587;20140276;16810345;28314744;28273376;28269762;28257752;28236475;28213687 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24090587/ PatentUS8337847