Peptide Database

Peptide NameIGF

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length3 amino acids

Chemical FormulaC17H25N3O4

DescriptionStandard

IGF

Molecular Weight335.40 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.44

Charge Density (pH 7.0) -0.0800

GRAVY Index2.30

Hydrophobic Moment 0.06

Boman Index1.02

Instability Index6.67

Aliphatic Index 130.00

Aromaticity 0.3333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 121.52

LogP 0.29

H-bond Donors 4.0

H-bond Acceptors 4.0

Rotatable Bonds 9.0

Heavy Atoms 24.0

Ring Count 1.0

Amide Bonds 2.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0140751 VERIFIED: YES

Provenance & Taxonomy

OrganismHippophae rhamnoides [Plant]

Familyseabuckthorn seed meal protein-derived peptide

Tax ID193516

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme inhibitory DPP-IV inhibitory Antidiabetic

TargetDPP-IV

Activity7.17 ± 0.14 mM

MethodIC50