MYP_077760
Ruminococcin A
Antimicrobial
Antimicrobial
▸
Antibacterial
Antimicrobial
▸
Antibacterial
▸
Anti-Gram-positive
Standard
24 amino acids
C119H180N32O35S4
Standard
GNGVLKTISHECNMNTWQFLFTCC
2747.16 Da
6.72
-0.18
-0.48
-0.0075
0.09
0.43
0.17
1.61
60.83
0.1250
5500.00
5625.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Amino Acid Composition
1093.69
-11.66
40.0
40.0
88.0
190.0
5.0
27.0
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0394558
VERIFIED: YES
Provenance & Taxonomy
Ruminococcus gnavus [Bacterium],Ruminococcus hansenii [Bacterium]
Bacteriocin
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
① It is highly probable that (i) Ser9 and the putative Cys23 and (ii) the putative His22 and Thr24 are associated in a Lanthionine (Lan) and a 3-methyllanthionine (Me-Lan) residue, respectively. ②The residues at position 7 and 16 are (Z)-2,3-didehydrobutyrine (Dhb)
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Bacillus cereus Z4222, TZ415
75 μg/mL
MIC
RECORD: Rec_0402228
VERIFIED: YES
Provenance & Taxonomy
Ruminococcus gnavus [Bacterium],Ruminococcus hansenii [Bacterium]
Bacteriocin
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
① It is highly probable that (i) Ser9 and the putative Cys23 and (ii) the putative His22 and Thr24 are associated in a Lanthionine (Lan) and a 3-methyllanthionine (Me-Lan) residue, respectively. ②The residues at position 7 and 16 are (Z)-2,3-didehydrobutyrine (Dhb)
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
Ruminococcus obeum ATCC 29174
32.5 μg/mL
MIC
RECORD: Rec_0404518
VERIFIED: YES
Provenance & Taxonomy
Ruminococcus gnavus [Bacterium],Ruminococcus hansenii [Bacterium]
Bacteriocin
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
① It is highly probable that (i) Ser9 and the putative Cys23 and (ii) the putative His22 and Thr24 are associated in a Lanthionine (Lan) and a 3-methyllanthionine (Me-Lan) residue, respectively. ②The residues at position 7 and 16 are (Z)-2,3-didehydrobutyrine (Dhb)
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
botulinum type B NCTC 7273
75 μg/mL
MIC
RECORD: Rec_0425502
VERIFIED: YES
Provenance & Taxonomy
Ruminococcus gnavus [Bacterium],Ruminococcus hansenii [Bacterium]
Bacteriocin
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
① It is highly probable that (i) Ser9 and the putative Cys23 and (ii) the putative His22 and Thr24 are associated in a Lanthionine (Lan) and a 3-methyllanthionine (Me-Lan) residue, respectively. ②The residues at position 7 and 16 are (Z)-2,3-didehydrobutyrine (Dhb)
Bio-Activity Profile
Antimicrobial
Antibacterial
Anti-Gram-positive
botulinum type A CIP 38
75 μg/mL
MIC
Showing 4 records on this page · Page 6 of 6