Peptide Database

Peptide NameTransforming growth factor alpha

Function Ontology

Mitogenic

Standard StatusStandard

Sequence Length50 amino acids

Chemical FormulaC240H357N71O71S6

DescriptionStandard

        VVSHFNQCPDSHTQFCFHGTCRFLVQEDKPACVCHSGYVGARCEHADLLA
    

Molecular Weight5565.23 Da

Isoelectric Point (pI)6.16

Net Charge (pH 7.0)-1.88

Net Charge (pH 7.4) -2.44

Charge Density (pH 7.0) -0.0377

GRAVY Index-0.08

Hydrophobic Moment 0.46

Boman Index0.06

Instability Index16.46

Aliphatic Index 60.40

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2245.10

LogP -24.90

H-bond Donors 82.0

H-bond Acceptors 80.0

Rotatable Bonds 174.0

Heavy Atoms 388.0

Ring Count 12.0

Amide Bonds 53.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0148852 VERIFIED: NO

Provenance & Taxonomy

OrganismOryctolagus cuniculus [Animal]

Tax ID9986

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-21; 16-32; 34-43

Bio-Activity Profile

Function

Mitogenic