Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length184 amino acids

Chemical FormulaC930H1473N253O248S8

DescriptionStandard

        PTPLPMAHEPMLVLAVTEFVANSAAFTYFTAGALRRNISSDMLPRQFPLQLSTKSMEVFSPQLQERYPDQPMELHLWARRQPLISCHPDALHGALFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTLTRNRLGGTVRLTGLVPTLSWTLPVPQVKRLETLLKFALWLFGVPRANSKCCPRPVP
    

Molecular Weight20422.71 Da

Isoelectric Point (pI)9.93

Net Charge (pH 7.0)7.29

Net Charge (pH 7.4) 6.97

Charge Density (pH 7.0) 0.0396

GRAVY Index0.06

Hydrophobic Moment 0.56

Boman Index0.10

Instability Index55.01

Aliphatic Index 94.89

Aromaticity 0.0815

Extinction Coeff. Reduced 19480.00

Extinction Coeff. Oxidized 19605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7855.49

LogP -88.75

H-bond Donors 271.0

H-bond Acceptors 267.0

Rotatable Bonds 638.0

Heavy Atoms 1439.0

Ring Count 43.0

Amide Bonds 197.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004149 VERIFIED: NO

Provenance & Taxonomy

OrganismPachycephala philippinensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria