Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length350 amino acids

Chemical FormulaC1806H2812N492O505S10

DescriptionStandard

        YPRRFGVAILKKELSTIKLPDFSGSFKVGWIKSVAYDFYRLKIHHFELRNSDLRLRPRQGVRASLSNNYVFISGNWKVKKAFVTLDGTFDVSVDDISISVSLNLGKDPSGRPTASVARCRNSIGHMSVDISGQLSWILNLFHERIENNFKNILEQKICEMVRKSTTSHLEPYLRTLPVTLMIDQIAGIDYSLVGAPQVNSQVLDTPFKGEFFGRNWRSPALFDAPSIRLPEKHDHMVYFAGSEYVFNTASWVYHQAGRMNFTIKNRHIPPDSPIRLHTSSFQAIAPRLSRMYPNMELELETTPESAPFLTFTPGNVTFMPVIDIQAFVLLPTSSDRKLLFQLRVTTNISA
    

Molecular Weight39817.29 Da

Isoelectric Point (pI)9.57

Net Charge (pH 7.0)10.64

Net Charge (pH 7.4) 9.83

Charge Density (pH 7.0) 0.0304

GRAVY Index-0.18

Hydrophobic Moment 0.72

Boman Index0.03

Instability Index36.95

Aliphatic Index 88.54

Aromaticity 0.1086

Extinction Coeff. Reduced 42400.00

Extinction Coeff. Oxidized 42525.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0375896 VERIFIED: NO

Provenance & Taxonomy

OrganismNeovison vison [Animal]

FamilyBPI/LBP

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence