Peptide Database

Peptide NameAP138 analog A24

Function Ontology

Antimicrobial

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC192H285N59O52S6

DescriptionStandard

        GFGCNGPWAEDDLRCHRHCKSIKGYRGGYCAKGGFVCKCY
    

Molecular Weight4444.07 Da

Isoelectric Point (pI)8.87

Net Charge (pH 7.0)3.87

Net Charge (pH 7.4) 3.47

Charge Density (pH 7.0) 0.0968

GRAVY Index-0.58

Hydrophobic Moment 0.46

Boman Index-0.09

Instability Index13.32

Aliphatic Index 31.75

Aromaticity 0.1500

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1788.27

LogP -18.80

H-bond Donors 70.0

H-bond Acceptors 64.0

Rotatable Bonds 143.0

Heavy Atoms 309.0

Ring Count 10.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0061828 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyPlectasin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-inflammatory

TargetS. agalactiae and Staphylococcus epidermidis. Warning: other bacteria not tested. Antimicrobial robustness: Peptide is active in 25% plasma

Activity4 μg/mL

MethodMIC

RECORD: Rec_0355482 VERIFIED: YES