‹ ›
MYP_077705
← PREVIOUS NEXT → BACK
Basic Information
Nigrocin-2JDa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Standard
21 amino acids
C92H160N24O23S2
Standard
Sequence
GIFGKILGAGKKVLCGLSGLC
Physicochemical Analysis
2034.53 Da
9.39
2.74
2.50
0.1303
1.10
0.52
0.41
-5.56
130.00
0.0476
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
743.61
-5.68
28.0
28.0
71.0
141.0
1.0
20.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0310602 VERIFIED: YES
Provenance & Taxonomy
Odorrana jingdongensis [Animal]
Nigrocin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
15-21
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus CIB 85462
8 μM
MIC
PMID22917879 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22917879/
RECORD: Rec_0316531 VERIFIED: YES
Provenance & Taxonomy
Odorrana jingdongensis [Animal]
Nigrocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Methicillin-resistant Staphylococcus aureus
16 μg/mL
MIC
PMID22917879 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22917879/
RECORD: Rec_0321194 VERIFIED: NO
Provenance & Taxonomy
Odorrana andersonii [Animal] [Animal]; Margaret frog [Animal] [Animal]; Odorrana jingdongensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0326413 VERIFIED: YES
Provenance & Taxonomy
Odorrana jingdongensis [Animal]
Nigrocin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
128 μg/mL
MIC
PMID22917879 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22917879/
RECORD: Rec_0326585 VERIFIED: YES
Provenance & Taxonomy
Odorrana andersonii [Animal]
Odorranain
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
15-21
Bio-Activity Profile
Antimicrobial Antibacterial
PaperJ. Li et al. / Molecular & Cellular Proteomics 6 (2007) 882-894. Anti-infection Peptidomics of Amphibian Skin PMID17272268 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17272268/
FIRST PREV 1 2 3 4 5 NEXT LAST
Showing 5 records on this page · Page 4 of 5