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MYP_077697
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Basic Information
Urotensin II
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasoconstrictor activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Vasoactive neuropeptide
Neurological / Signaling ▸ Sleep regulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Standard
14 amino acids
C76H105N19O19S2
Standard
Sequence
QHGAAPECFWKYCI
Physicochemical Analysis
1652.89 Da
6.73
-0.17
-0.46
-0.0123
-0.17
0.30
0.18
53.37
42.14
0.2143
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
603.94
-3.08
22.0
22.0
48.0
116.0
6.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0045726 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Urotensin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
8-13
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular ACE inhibitory Sleep regulation Wake regulation
hela
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Urotensin II (Mus musculus): PMID 31238319 PMID31238319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31238319/
RECORD: Rec_0076196 VERIFIED: NO
Provenance & Taxonomy
Mus musculus [Animal]
Urotensin-2
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
8-13
Bio-Activity Profile
Hormone Vasoactive neuropeptide
RECORD: Rec_0109472 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 28.6%, E 0.0%, T 28.6%, C 42.9% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0113576 VERIFIED: YES
Provenance & Taxonomy
Mus musculus [Animal]
Urotensin
10090
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
8-13
Bio-Activity Profile
Hormone Endocrine Vasoactive Vasoconstrictor Cardiovascular ACE inhibitory Sleep regulation Wake regulation
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Urotensin II (Mus musculus): PMID 31238319 PMID31238319 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31238319/
RECORD: Rec_0357816 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/