Peptide Database

Peptide NameDermaseptin DRG1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antifungal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC140H238N40O42

DescriptionStandard

        GLWSNIKTAGKEAAKAALKAAGKAALGAVTDAV
    

Molecular Weight3153.63 Da

Isoelectric Point (pI)9.83

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.0836

GRAVY Index0.28

Hydrophobic Moment 0.60

Boman Index0.18

Instability Index14.75

Aliphatic Index 98.18

Aromaticity 0.0303

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1318.79

LogP -14.51

H-bond Donors 46.0

H-bond Acceptors 45.0

Rotatable Bonds 107.0

Heavy Atoms 222.0

Ring Count 2.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0267071 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)

RECORD: Rec_0313500 VERIFIED: NO

Provenance & Taxonomy

OrganismAmerican frog [Animal]