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MYP_077594
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Basic Information
12530
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
11 amino acids
C73H114N16O13
Standard
Sequence
KFKKVIWKSFL
Physicochemical Analysis
1423.79 Da
10.48
3.76
3.55
0.3415
0.07
0.47
0.05
-12.29
97.27
0.2727
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
494.42
0.71
18.0
17.0
49.0
102.0
4.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0002407 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human RBC High haemolytic activity, lysing approximately 50% of erythrocytes at concentrations of 50 microM
50 μM
Hemolysis
PMID31302447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31302447/
RECORD: Rec_0197188 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
C. trachomatis D/UW-3/Cx
12.5 μM
MIC90
PaperMedicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens
RECORD: Rec_0258221 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli MG1655
90 μM
MIC
PMID31302447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31302447/
RECORD: Rec_0301236 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli MG1655
90 μM
MIC
PaperMedicinal leech antimicrobial peptides lacking toxicity represent a promising alternative strategy to combat antibiotic-resistant pathogens
RECORD: Rec_0332740 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
C. trachomatis D/UW-3/Cx MIC90 = 12.5 microM
PMID31302447 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/31302447/
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