Peptide Database

Peptide NameCrustacean hyperglycemic hormone

Function Ontology

Developmental biology ▸ Molting regulation

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC372H581N99O111S6

DescriptionStandard

        QVFDQACKGIYDRAIFKKLDRVCDDCYNLYRKPYVATTCRQNCYANSVFRQCLDDLLLIDVVDEYISGVQIV
    

Molecular Weight8408.58 Da

Isoelectric Point (pI)5.07

Net Charge (pH 7.0)-1.30

Net Charge (pH 7.4) -1.61

Charge Density (pH 7.0) -0.0180

GRAVY Index-0.07

Hydrophobic Moment 0.80

Boman Index-0.03

Instability Index18.08

Aliphatic Index 97.36

Aromaticity 0.1250

Extinction Coeff. Reduced 8940.00

Extinction Coeff. Oxidized 9315.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3454.23

LogP -29.91

H-bond Donors 125.0

H-bond Acceptors 116.0

Rotatable Bonds 278.0

Heavy Atoms 588.0

Ring Count 10.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0304987 VERIFIED: NO

Provenance & Taxonomy

OrganismAstacus astacus [Animal]

FamilyCrustacean hyperglycemic hormone

Tax ID6715

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

ChiralityD-residue-containing modified peptide [Mixed]

N-TermPyroglutamate

C-TermAmidation

Disulfide7-43; 23-39; 26-52

Other Mods3:D-phenylalanine

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Molting regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour