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MYP_077467
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antifungal
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Sensory / Food function ▸ Taste-active peptide
Standard
2 amino acids
C10H18N2O3
Standard
Sequence
VP
Physicochemical Analysis
214.26 Da
5.50
-0.27
-0.48
-0.1330
1.30
0.53
0.60
101.30
145.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
83.63
0.05
2.0
3.0
3.0
15.0
1.0
1.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0095511 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; Sardine fermented [Plant]; Glycine max [Plant]; Sus scrofa [Animal]; Gallus gallus [Animal]; Actinopterygii [Animal]; Poaceae [Plant]; Fabaceae [Plant]
9913; 33090; 3847; 9823; 9031; 7898; 4479; 3803
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
PaperStructural requirements of Angiotensin I-converting enzyme inhibitory peptides: quantitative structure-activity relationship study of di- and tripeptides PMID16448176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16448176/
RECORD: Rec_0107284 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
20000 μM
IC50
PaperStructural requirements of Angiotensin I-converting enzyme inhibitory peptides: quantitative structure-activity relationship study of di- and tripeptides. PMID16448176 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16448176/
RECORD: Rec_0108439 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Conjugate type: amide; Conjugated small molecule: Cytarabine
Bio-Activity Profile
-
PaperApplication of the Dipeptidyl Peptidase IV (DPPIV/CD26) Based Prodrug Approach to Different Amine-Containing Drugs PMID20000418 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20000418/
RECORD: Rec_0120098 VERIFIED: YES
Provenance & Taxonomy
Glycine max [Plant]
3847
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Spontaneously hypertensive rats (SHR)
480 μg/mL
IC50
PaperAntihypertensive effect of peptide-enriched soy sauce-like seasoning and identification of its angiotensin I-converting enzyme inhibitory substances PMID19994857 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19994857/
RECORD: Rec_0153175 VERIFIED: YES
Provenance & Taxonomy
Hordeum vulgare [Plant]; Glycine max [Plant]
ACE inhibitory peptide
4513, 3847
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Taste ACE inhibitory Antihypertensive
Angiotensin-converting enzyme
10-1100 μg/mL
IC50
PaperIsolation and characterization of peptides with antihypertensive activity in foodstuffs | Vegetable foods: a cheap source of proteins and peptides with antihypertensive, antioxidant, and other less occurrence bioactivities PMID24915368;23598130 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24915368/
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