Peptide Database

Peptide NameDermaseptin-PH

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Standard StatusStandard

Sequence Length44 amino acids

Chemical FormulaC226H371N57O78S4

DescriptionStandard

        MDILKKSLFLILFLGVVSLSICEEEKRENEEEMEQDDEQSEMKR
    

Molecular Weight5262.96 Da

Isoelectric Point (pI)4.31

Net Charge (pH 7.0)-7.48

Net Charge (pH 7.4) -7.74

Charge Density (pH 7.0) -0.1700

GRAVY Index-0.58

Hydrophobic Moment 0.42

Boman Index-0.15

Instability Index88.55

Aliphatic Index 92.95

Aromaticity 0.0455

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2237.59

LogP -18.23

H-bond Donors 76.0

H-bond Acceptors 75.0

Rotatable Bonds 193.0

Heavy Atoms 365.0

Ring Count 2.0

Amide Bonds 46.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0330330 VERIFIED: YES

Provenance & Taxonomy

OrganismPithecopus hypochondrialis [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetPseudomonas aeruginosa

Activity64 μM

MethodMIC

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