Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length114 amino acids

Chemical FormulaC550H891N149O162S4

DescriptionStandard

        PDLTGHEKFGLGNVKYNISGIHITAVELPSASISLLPGSGIKLVIGNASLTINMNWNIRTWMFKDSGRSTVHISKVFVTAIFSTPLDNIGPTLMSLTSCRTTPGDIDIKLNRKS
    

Molecular Weight12311.12 Da

Isoelectric Point (pI)9.59

Net Charge (pH 7.0)4.21

Net Charge (pH 7.4) 3.97

Charge Density (pH 7.0) 0.0370

GRAVY Index0.09

Hydrophobic Moment 0.54

Boman Index0.14

Instability Index38.10

Aliphatic Index 100.88

Aromaticity 0.0614

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4952.61

LogP -52.82

H-bond Donors 175.0

H-bond Acceptors 173.0

Rotatable Bonds 406.0

Heavy Atoms 865.0

Ring Count 18.0

Amide Bonds 121.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0191398 VERIFIED: NO

Provenance & Taxonomy

OrganismGrallaria varia [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria