Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length119 amino acids

Chemical FormulaC596H941N161O170S3

DescriptionStandard

        EGLSVFRSLVFFDTQPNISISVFYRIRINAVDFPETSASFIPGTGISLSVARASATITADWRMNTWLLKDQGRMTVYISGLFIEVIFKVSRDSTGHLSVLLHNCQLHLNSVKVKLNGGS
    

Molecular Weight13178.02 Da

Isoelectric Point (pI)9.43

Net Charge (pH 7.0)3.09

Net Charge (pH 7.4) 2.74

Charge Density (pH 7.0) 0.0260

GRAVY Index0.25

Hydrophobic Moment 0.69

Boman Index0.15

Instability Index18.15

Aliphatic Index 103.95

Aromaticity 0.1008

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 13980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 5317.71

LogP -52.55

H-bond Donors 190.0

H-bond Acceptors 179.0

Rotatable Bonds 433.0

Heavy Atoms 930.0

Ring Count 20.0

Amide Bonds 127.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0235841 VERIFIED: NO

Provenance & Taxonomy

OrganismCeuthmochares aereus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria