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MYP_077246
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Basic Information
Caerin 1.11
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
25 amino acids
C126H201N31O30S
Standard
Sequence
GLLGAMFKVASKVLPHVVPAITEHF
Physicochemical Analysis
2662.20 Da
8.61
0.94
0.63
0.0374
0.90
0.58
0.41
17.05
120.80
0.0800
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
931.30
-4.16
31.0
34.0
83.0
188.0
6.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010997 VERIFIED: YES
Provenance & Taxonomy
Litoria eucnemis [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID15752569 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15752569/
RECORD: Rec_0011191 VERIFIED: YES
Provenance & Taxonomy
Litoria caerulea [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Enterobacter cloacae
50 μM
MIC
PMID12709067;22771617 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12709067/
RECORD: Rec_0076660 VERIFIED: YES
Provenance & Taxonomy
Litoria eucnemis [Animal]
Caerin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperM.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance PMID15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15203252/
RECORD: Rec_0109644 VERIFIED: YES
Provenance & Taxonomy
Litoria caerulea [Animal]
Structure & Mods
DNA-encoded linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0169820 VERIFIED: YES
Provenance & Taxonomy
Litoria caerulea [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
25 μM
MIC
PMID12709067;22771617 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12709067/
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