Peptide Database

Peptide NameDs-defensin

Function Ontology

Antimicrobial

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC146H246N42O45S6

DescriptionStandard

        GGCPDADKCTKYCQKQGISVGKCAKPVNACVCIL
    

Molecular Weight3502.16 Da

Isoelectric Point (pI)8.64

Net Charge (pH 7.0)2.70

Net Charge (pH 7.4) 2.40

Charge Density (pH 7.0) 0.0793

GRAVY Index0.04

Hydrophobic Moment 0.49

Boman Index0.03

Instability Index38.44

Aliphatic Index 68.82

Aromaticity 0.0294

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1400.70

LogP -17.00

H-bond Donors 52.0

H-bond Acceptors 54.0

Rotatable Bonds 116.0

Heavy Atoms 239.0

Ring Count 3.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0321593 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antioxidant

TargetP. faecalis

Activity25 μM

MethodMIC

RECORD: Rec_0323188 VERIFIED: YES