Peptide Database

Peptide NameAntimicrobial peptide 1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC61H113N19O14

DescriptionStandard

        LRPAVIVRTKAL
    

Molecular Weight1336.67 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.2299

GRAVY Index0.74

Hydrophobic Moment 0.20

Boman Index0.03

Instability Index50.24

Aliphatic Index 162.50

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 544.68

LogP -3.24

H-bond Donors 20.0

H-bond Acceptors 17.0

Rotatable Bonds 43.0

Heavy Atoms 94.0

Ring Count 1.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0032696 VERIFIED: NO

Provenance & Taxonomy

OrganismPithecopus hypochondrialis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-positive bacteria

MethodQualitative functional evidence

RECORD: Rec_0046477 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0079135 VERIFIED: NO

Provenance & Taxonomy

OrganismPhyllomedusa hypochondrialis [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

TargetMicrococcus luteus

RECORD: Rec_0138508 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa hypochondrialis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetMicrococcus luteus

RECORD: Rec_0165683 VERIFIED: YES

Provenance & Taxonomy

OrganismPhyllomedusa hypochondrialis [Animal]

FamilyAntimicrobial

Structure & Mods

Configribosomal mature linear peptide [Linear]

ChiralityGene-encoded natural peptide composed of standard L-amino acids [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal