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MYP_077168
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Basic Information
Longipin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
18 amino acids
C104H152N22O26
Standard
Sequence
SGYLPGKEYVYKYKGKVF
Physicochemical Analysis
2126.45 Da
9.52
2.46
2.23
0.1364
-0.72
0.36
0.01
-7.63
53.89
0.2778
5960.00
5960.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
791.76
-3.19
28.0
29.0
68.0
152.0
6.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0174040 VERIFIED: YES
Provenance & Taxonomy
Acutisoma longipes [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Pseudomonas aeruginosa ATCC 27853
60-120 μM
MIC
PaperLongipin: An Amyloid Antimicrobial Peptide from the Harvestman Acutisoma longipes (Arachnida: Opiliones) with Preferential Affinity for Anionic Vesicles
RECORD: Rec_0177238 VERIFIED: YES
Provenance & Taxonomy
Acutisoma longipes [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
C.herbarum ATCC 26362
>120 μM
MIC
PaperLongipin: An Amyloid Antimicrobial Peptide from the Harvestman Acutisoma longipes (Arachnida: Opiliones) with Preferential Affinity for Anionic Vesicles
RECORD: Rec_0190399 VERIFIED: YES
Provenance & Taxonomy
hemolymph,Acutisoma longipes [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antifungal
Candida tropicalis
3.8-7.5 μM
MIC
PMID27997568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27997568/
RECORD: Rec_0191313 VERIFIED: YES
Provenance & Taxonomy
hemolymph,Acutisoma longipes [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antifungal
Candida albicans IOC4558 (7.5-15 uM)
PMID27997568 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27997568/
RECORD: Rec_0196459 VERIFIED: YES
Provenance & Taxonomy
Acutisoma longipes [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli D31 or SBS363
>120 μM
MIC
PaperLongipin: An Amyloid Antimicrobial Peptide from the Harvestman Acutisoma longipes (Arachnida: Opiliones) with Preferential Affinity for Anionic Vesicles
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