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MYP_077151
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Basic Information
TSP-1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Anti-angiogenic
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ FGF2-binding antiangiogenic template
Standard
15 amino acids
C67H101N21O36
Standard
Sequence
DDDDDNDKIPDDRDN
Physicochemical Analysis
1776.64 Da
4.05
-7.23
-7.44
-0.4821
-2.93
0.27
-0.81
-13.96
26.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
971.73
-13.85
30.0
29.0
60.0
124.0
1.0
16.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0211273 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID20056600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20056600/
RECORD: Rec_0216413 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0217713 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Thrombospondin-1
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
FGF2-binding antiangiogenic template
FGF2 pathway
FGF2-binding assay
PaperNon-peptidic Thrombospondin-1 Mimics as Fibroblast Growth Factor-2 Inhibitors PMID20056600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20056600/
RECORD: Rec_0228882 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID20056600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20056600/
RECORD: Rec_0255345 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Anticancer Anti-angiogenic
PaperAntiAngioPred: A Server for Prediction of Anti-Angiogenic Peptides PMID26335203 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26335203/
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