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MYP_077103
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
40 amino acids
C197H325N71O48S6
Standard
Sequence
VRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW
Physicochemical Analysis
4648.52 Da
11.20
8.76
8.41
0.2190
-0.32
0.76
-0.22
26.00
60.75
0.0750
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1947.73
-22.36
78.0
64.0
148.0
322.0
8.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0298409 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus 502A
10-300 μg/mL
MIC
PMID8454635 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8454635/
RECORD: Rec_0340816 VERIFIED: NO
Provenance & Taxonomy
Bubalus bubalis [Animal]
Defensin
89462
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal
Qualitative functional evidence
PMID18826332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18826332/; https://www.uniprot.org/uniprotkb/P85150/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0342688 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperSelsted M.E., Tang Y.-Q., Morris W.L., McGuire P.A., Novotny M.J., Smith W., Henschen A.H., Cullor J.S.;. "Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils."; J. Biol. Chem. 268:6641-6648. Evidence URLhttps://www.uniprot.org/uniprotkb/BD02_BOVIN/entry
RECORD: Rec_0409459 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; Bubalus bubalis [Animal]
Defensin
9913
Structure & Mods
disulfide-stabilized linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-36; 14-29; 19-37
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0410269 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
7-29; 14-36; 19-37
Bio-Activity Profile
Antimicrobial
PMID16777238 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16777238/
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