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MYP_077103
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
40 amino acids
C197H325N71O48S6
Standard
Sequence
VRNHVTCRINRGFCVPIRCPGRTRQIGTCFGPRIKCCRSW
Physicochemical Analysis
4648.52 Da
11.20
8.76
8.41
0.2190
-0.32
0.76
-0.22
26.00
60.75
0.0750
5500.00
5875.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1947.73
-22.36
78.0
64.0
148.0
322.0
8.0
42.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0027906 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US5459235A/en PatentUS 5459235 A
RECORD: Rec_0029521 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Beta-defensin; Defensin
9913
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
disulfide bond; sites not specified
Bio-Activity Profile
Antimicrobial Defensin Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Staphylococcus aureus
PMID8454635 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8454635/
RECORD: Rec_0108493 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 15.0%, E 35.0%, T 25.0%, C 25.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial Anti-Gram-positive Anti-Gram-negative
PaperCAMP: Collection of sequences and structures of antimicrobial peptides PMID24265220 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24265220/
RECORD: Rec_0116816 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Escherichia coli D31, Pseudomonas aeruginosa PAO1
62 μg/mL
MIC
PaperPurification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.
RECORD: Rec_0147106 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
Defensin
9913
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
stereochemistry not specified [Other]
Disulfide bond(s) reported
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ML35
10-300 μg/mL
MIC
PMID8454635 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8454635/
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