Peptide Database

Peptide NamePyocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length568 amino acids

Chemical FormulaC2777H4384N814O828S23

DescriptionStandard

        MTYRPDIHGRGMALSCDKTTTGAWLITSLPVPNYNVCGNGLIRKGDKTTPCPACGKPGMVAEGEARFKVIDIPIAVDGCVVHCGCPEGSNRIIAPLGQWMGAGPSPAEIAQKKQAELIAQRKAEREAEEKRREEERERNRVFAKSCLRGEGCNDAGDQREPHTNFAPMGIYQAVPQTDPVTDTEAPQRAQAVKKKKLIAPEDIPKPKKRSALWKWWNGHHEEMDYQRAVEEAERAQRARAAIAGASVLHPVAGNFAIRGTWAVVGETATGVAGLPLAAFLIGMMPGRLNDGEQDFIDRMRAEQAREVPTRVRFTWETNSRGNPVPHGWHTPPGQDRVRVRRMEWDDRRKAYTFTTEEDPRITLIWTPDNPGIDVPNHTGNQYPPVLPNPVMVDPLPDDTGLHATTSPAPEEKDFADYILILPFPDIPPIYIYLSKPPVEFLEVELYSDFKRRSRQGKYEADHMPSRAAVDAYLRANYPLLDDAEILVLTDQVAAIVVPKEVHQRLSETYGGRNTPAQIELDSRNLRAAVDRNLDAIKPALKEHGATEGQIEAARAKMHKLNSGMGLYK
    

Molecular Weight63158.97 Da

Isoelectric Point (pI)6.57

Net Charge (pH 7.0)-2.25

Net Charge (pH 7.4) -3.47

Charge Density (pH 7.0) -0.0040

GRAVY Index-0.59

Hydrophobic Moment 0.77

Boman Index-0.09

Instability Index42.17

Aliphatic Index 73.24

Aromaticity 0.0651

Extinction Coeff. Reduced 77350.00

Extinction Coeff. Oxidized 77850.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0081157 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia sp. E4742 [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)