Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length264 amino acids

Chemical FormulaC1342H2110N334O391S7

DescriptionStandard

        MEKPILKNLNKMLCPIITSEVEALNANLSMLKALRKIDNYTLLDYSLISSPEITENYVDLNLKGVFYPLENLTDTPFSSVPFVLPEHSDSMIYIGISEYFFKSASYAYFTAGAFNVTLTTKEIFNHLIRNSQGLGSMLSQVASTNVALAILGQRLICSLSLKSFYLSLPESSRSNTEVLRFENILSSILHFGVLPLANAKLQQGFPLPNPQNISLVNSDIEVLEGFVLISTDLKYKTSLKQQPSFHGWEALNLISGQWRGKPAP
    

Molecular Weight29403.57 Da

Isoelectric Point (pI)6.10

Net Charge (pH 7.0)-2.14

Net Charge (pH 7.4) -2.66

Charge Density (pH 7.0) -0.0081

GRAVY Index0.09

Hydrophobic Moment 0.69

Boman Index0.15

Instability Index46.82

Aliphatic Index 106.74

Aromaticity 0.0985

Extinction Coeff. Reduced 25900.00

Extinction Coeff. Oxidized 26025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0060506 VERIFIED: NO

Provenance & Taxonomy

OrganismBalaenoptera musculus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria