Peptide Database

Peptide NameSLAY-screened peptide P414

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC33H55N9O9S

DescriptionStandard

        ALRTMY
    

Molecular Weight753.91 Da

Isoelectric Point (pI)8.79

Net Charge (pH 7.0)0.79

Net Charge (pH 7.4) 0.61

Charge Density (pH 7.0) 0.1325

GRAVY Index0.17

Hydrophobic Moment 0.66

Boman Index0.00

Instability Index79.90

Aliphatic Index 81.67

Aromaticity 0.1667

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 311.18

LogP -1.77

H-bond Donors 12.0

H-bond Acceptors 11.0

Rotatable Bonds 23.0

Heavy Atoms 52.0

Ring Count 1.0

Amide Bonds 5.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0035035 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/