Peptide Database

Peptide NameSLAY-screened peptide P644

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC72H112N16O23S

DescriptionStandard

        NLCFSSLDSFITAAL
    

Molecular Weight1601.82 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.25

Net Charge (pH 7.4) -1.47

Charge Density (pH 7.0) -0.0832

GRAVY Index1.17

Hydrophobic Moment 0.38

Boman Index0.41

Instability Index35.01

Aliphatic Index 117.33

Aromaticity 0.1333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 632.03

LogP -6.47

H-bond Donors 23.0

H-bond Acceptors 23.0

Rotatable Bonds 50.0

Heavy Atoms 112.0

Ring Count 2.0

Amide Bonds 15.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0232155 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/