Peptide Database

Peptide NamepQDPFLRFamide

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC44H62N10O12

DescriptionStandard

        EDPFLRF
    

Molecular Weight923.02 Da

Isoelectric Point (pI)4.37

Net Charge (pH 7.0)-1.16

Net Charge (pH 7.4) -1.33

Charge Density (pH 7.0) -0.1660

GRAVY Index-0.53

Hydrophobic Moment 0.63

Boman Index-0.09

Instability Index91.11

Aliphatic Index 55.71

Aromaticity 0.2857

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 365.63

LogP -1.05

H-bond Donors 12.0

H-bond Acceptors 11.0

Rotatable Bonds 27.0

Heavy Atoms 66.0

Ring Count 3.0

Amide Bonds 6.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0042752 VERIFIED: YES

Provenance & Taxonomy

OrganismHelix aspersa [Animal]

FamilyFMRFamide related peptide

Tax ID6535

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0330251 VERIFIED: YES

Provenance & Taxonomy

OrganismCornu aspersum [Animal]

FamilypQDPFLRFamide

Tax ID6535

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

-

Half-LifeMammalian: 1 hour; Yeast: 30 min; E. coli: >10 hour

RECORD: Rec_0356386 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyFMRFamide-like peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/