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MYP_076975
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Basic Information
c-Muscin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
25 amino acids
C134H218N42O36S2
Standard
Sequence
EWKLPDLIINHITLTRRNCNKYRCG
Physicochemical Analysis
3057.55 Da
9.39
2.90
2.65
0.1161
-0.71
0.52
-0.22
51.86
93.60
0.0800
6990.00
7115.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1299.70
-11.28
48.0
42.0
101.0
214.0
5.0
27.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0259604 VERIFIED: YES
Provenance & Taxonomy
Musca Domestica [Animal]
Muscin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PaperActa Entomologica Sinica 2015 June; 58(6): 617-614. | http://www.insect.org.cn/CN/abstract/abstract14103.shtml
RECORD: Rec_0261675 VERIFIED: YES
Provenance & Taxonomy
Musca domestica [Animal]
Muscin
7370
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Sporosarcina ureae
164 μM
MIC
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37362
RECORD: Rec_0263349 VERIFIED: YES
Provenance & Taxonomy
Musca domestica [Animal]
Muscin
7370
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas fluorescens
32.7 μM
MIC
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP37362
RECORD: Rec_0265925 VERIFIED: YES
Provenance & Taxonomy
Musca domestica [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0276702 VERIFIED: YES
Provenance & Taxonomy
House fly [Animal]; Insecta [Animal]
33208; 50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID24747431 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24747431/
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