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MYP_076911
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Basic Information
Maximin H4
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
20 amino acids
C93H167N23O23
Standard
Sequence
ILGPVIKTIGGVIGGLLKNL
Physicochemical Analysis
1975.46 Da
10.00
1.76
1.55
0.0879
1.30
0.46
0.53
32.61
185.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
722.79
-3.53
24.0
25.0
67.0
139.0
1.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014518 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Maximin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0055620 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0072976 VERIFIED: YES
Provenance & Taxonomy
Firebelly toad [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID21338048 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21338048/
RECORD: Rec_0082583 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Maximin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
PaperVariety of antimicrobial peptides in the Bombina maxima toad and evidence of their rapid diversification. Eur J Immunol. 2005 Apr;35(4):1220-1229. doi: 10.1002/eji.200425615. PMID: 15770703. PMID15770703 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15770703/
RECORD: Rec_0111886 VERIFIED: YES
Provenance & Taxonomy
Bombina maxima [Animal]
Maximin
161274
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
shows strong hemolytic activity
Hemolysis
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ1780
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