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MYP_076880
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Basic Information
Rhesus macaque oral alpha-defensins (ROADs; primates, mammals, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
32 amino acids
C145H251N61O44S6
Standard
Sequence
RRTCHCRSRCLRRESNSGSCNINGRIFSLCCR
Physicochemical Analysis
3745.32 Da
10.44
6.79
6.45
0.2122
-0.76
0.67
-0.50
112.70
48.75
0.0312
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1777.25
-27.40
74.0
58.0
128.0
256.0
2.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0029319 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
9544
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-31; 6-20; 10-30
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Staphylococcus aureus
PaperPubMed PMID: 18930922 PMID18930922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18930922/
RECORD: Rec_0152245 VERIFIED: NO
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli, Staphylococcus aureus, C. albicans
RECORD: Rec_0203053 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Staphylococcus aureus, Escherichia coli
PaperSynthesis, structure and activities of an oral mucosal alpha-defensin from rhesus macaque.
RECORD: Rec_0217683 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus
PMID18930922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18930922/
RECORD: Rec_0222214 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
9544
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-31; 6-20; 10-30
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans
PaperPubMed PMID: 18930922 PMID18930922 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18930922/
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