Peptide Database

Peptide NameSLAY-screened peptide P3668

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC112H170N32O28S

DescriptionStandard

        RWLLPTAVNNCISTPVFWRGN
    

Molecular Weight2444.81 Da

Isoelectric Point (pI)10.35

Net Charge (pH 7.0)1.75

Net Charge (pH 7.4) 1.53

Charge Density (pH 7.0) 0.0833

GRAVY Index0.02

Hydrophobic Moment 0.39

Boman Index0.12

Instability Index51.56

Aliphatic Index 88.10

Aromaticity 0.1429

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 973.08

LogP -8.26

H-bond Donors 35.0

H-bond Acceptors 31.0

Rotatable Bonds 71.0

Heavy Atoms 173.0

Ring Count 7.0

Amide Bonds 23.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0365802 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/