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MYP_076821
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Basic Information
P2
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
20 amino acids
C116H180N28O24
Standard
Sequence
KWKLFKKIGIGKFLHSATTF
Physicochemical Analysis
2350.84 Da
10.60
4.84
4.58
0.2421
0.01
0.49
0.13
-8.82
83.00
0.2000
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
851.48
-3.11
31.0
30.0
80.0
168.0
6.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0240361 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 10.0%, T 40.0%, C 50.0% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer Antibacterial Antimicrobial
PaperCancerPPD: a database of anticancer peptides and proteins PMID25270878 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25270878/
RECORD: Rec_0242445 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0280581 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
CA-MA / CA-ME / cecropin-magainin hybrid
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
NCI-H69
36.2 μM
IC50 / MTT-MTS assay
PaperPMID 9352466; CA-MA/CA-ME analog P2 report PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
RECORD: Rec_0286249 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]
Magainin
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
RECORD: Rec_0316101 VERIFIED: YES
Provenance & Taxonomy
Ceropin A-Magainin 2 [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
NCI-H69
36.2 μM
IC50
PaperPubMed PMID: 9352466 PMID9352466 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9352466/
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