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MYP_076812
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Basic Information
Cecropin-A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
37 amino acids
C185H318N56O45
Standard
Sequence
RWKLFKKIEKVGRNVRDGLIKAGPAIAVIGQAKSLGK
Physicochemical Analysis
4046.85 Da
11.20
7.76
7.54
0.2096
-0.22
0.91
-0.07
27.80
108.11
0.0541
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1666.77
-12.98
59.0
53.0
144.0
286.0
4.0
38.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0009226 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
Cecropin
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 22108
6.25 μg/mL
MIC
PMID32322274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32322274/
RECORD: Rec_0034543 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
Cecropin
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 33591
500 μg/mL
MIC
PMID32322274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32322274/
RECORD: Rec_0055410 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
Cecropin
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human hepatocellular carcinoma HepG2
100 μg/mL
PMID32322274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32322274/
RECORD: Rec_0191863 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0211495 VERIFIED: YES
Provenance & Taxonomy
Bombyx mori [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 32322274 PMID32322274 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32322274/
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