Peptide Database

Peptide NameKnot1 domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length80 amino acids

Chemical FormulaC397H613N103O103S11

DescriptionStandard

        MAKFASIVPMLFVVLVLFAAFEAPAMVDAQKLCTRVSKTWSGVCGSNGACKNQCINLEKARHGSCNYIFPYHKCVCYFPC
    

Molecular Weight8829.46 Da

Isoelectric Point (pI)8.87

Net Charge (pH 7.0)4.59

Net Charge (pH 7.4) 4.14

Charge Density (pH 7.0) 0.0574

GRAVY Index0.45

Hydrophobic Moment 0.64

Boman Index0.20

Instability Index29.18

Aliphatic Index 79.25

Aromaticity 0.1250

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3252.87

LogP -27.04

H-bond Donors 119.0

H-bond Acceptors 121.0

Rotatable Bonds 281.0

Heavy Atoms 614.0

Ring Count 17.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0236360 VERIFIED: NO

Provenance & Taxonomy

OrganismArabis alpina [Plant]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicide Non-hemolytic Non-ribosomal

MethodQualitative functional evidence