Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length87 amino acids

Chemical FormulaC414H638N114O124S11

DescriptionStandard

        MAFSVADAVAVVLTCTFILESTAVPSSEVLTEEVGSFDSPVGEHQQPGGESMRLPEPFRFKRQSHLSLCRWCCNCCHNKGCGFCCKF
    

Molecular Weight9548.90 Da

Isoelectric Point (pI)5.83

Net Charge (pH 7.0)-2.31

Net Charge (pH 7.4) -2.82

Charge Density (pH 7.0) -0.0265

GRAVY Index0.07

Hydrophobic Moment 0.49

Boman Index0.08

Instability Index80.67

Aliphatic Index 63.79

Aromaticity 0.0920

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3763.60

LogP -41.28

H-bond Donors 138.0

H-bond Acceptors 136.0

Rotatable Bonds 306.0

Heavy Atoms 663.0

Ring Count 17.0

Amide Bonds 91.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0237627 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmo trutta [Animal]

FamilyHepcidin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal