Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length458 amino acids

Chemical FormulaC2270H3531N573O673S18

DescriptionStandard

        MKAVVFQRNNTVYLSKRALSMLSLLILLLNLTNHAFGENPAIKAILTNKGLQYGSHIGADWMQEKIWSMIIPDISGGVDIGIGTVHYVLDGISVSGCDVPEPSVEFYEGVGLKTGISGFSISMKGNWHTRFGIISDGGSFDLAVFNVDVTSVVQLGSDYSGHISISSENCDARISKASITFHGGASFIFQPFVTLFKDQMTALIEEKICPMVEEHVTDLDQHLAEMQVSFKVNSALVLDIPLTNPPLVESIGLGLDLKGEFYSVQSHTDPPFKAEHFDLPKDDGHMLSLGLSEFTVNSASYGYFSAGLLQAKINDSMIPKTSPFRLNTTSFGPLIPQLPKLFPNMLMELQVYARDVPMFSFQADKVTQEFPGAIKAFAIQPNASRTPLFNLNVDSIFRGMIRISEEKLQGLMKLNNFTLTLASSEVGTFQGFVSIASDLDVKSAERESISEGIYPYQL
    

Molecular Weight50193.92 Da

Isoelectric Point (pI)5.10

Net Charge (pH 7.0)-15.51

Net Charge (pH 7.4) -16.43

Charge Density (pH 7.0) -0.0339

GRAVY Index0.10

Hydrophobic Moment 0.82

Boman Index0.17

Instability Index27.59

Aliphatic Index 95.13

Aromaticity 0.0961

Extinction Coeff. Reduced 32890.00

Extinction Coeff. Oxidized 33015.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0102829 VERIFIED: NO

Provenance & Taxonomy

OrganismCoregonus sp. `balchen` [Bacterium]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria