Peptide Database

Peptide NameInsulin A chain

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length21 amino acids

Chemical FormulaC101H163N33O31S4

DescriptionStandard

        GIVEQCCHRPCNIRVLENYCN
    

Molecular Weight2463.84 Da

Isoelectric Point (pI)6.72

Net Charge (pH 7.0)-0.19

Net Charge (pH 7.4) -0.50

Charge Density (pH 7.0) -0.0089

GRAVY Index-0.25

Hydrophobic Moment 0.47

Boman Index-0.10

Instability Index49.05

Aliphatic Index 83.33

Aromaticity 0.0476

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1740.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1056.20

LogP -11.54

H-bond Donors 39.0

H-bond Acceptors 36.0

Rotatable Bonds 79.0

Heavy Atoms 169.0

Ring Count 3.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124844 VERIFIED: YES

Provenance & Taxonomy

OrganismMyoxocephalus scorpius [Animal]

FamilyInsulin

Tax ID8097

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide6-11

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour